CASES OF ISOLATED SKIN AND NAIL ASPERGILLOSIS AND SECONDARY
ASPERGILLOUS SKIN LESION CAUSED BY AN OCCUPATIONAL FACTOR.
SYMPTOM OF «DRIED LEAVES» FOR NAIL ASPERGILLOSIS

About the author:	Kravchenko V.G., Kravchenko A.V.	
Heading	CLINICAL CASES	
Type of article	Scientific Article	
Annotation	Cases of aspergillosis (A.), both isolated lesions of the skin and nails, and secondary 
skin lesions as a result of complications of invasive aspergillosis of the lungs and 
intestines, can be considered occupational, since there is a clear connection with 
the direct professional activities of the patients. it was found. It can be assumed that 
A. of the skin and nails in dermatological practice occurs more often than is
 diagnosed, especially since at the present stage the total number of patients with
 fungal infection is increasing.
The goal is to share the experience of clinical and laboratory diagnostics and 
effective treatment of patients with isolated lesions of the skin and nails due to 
aspergillosis.
Materials and methods. A clinical case of skin damage due to invasive aspergillosis 
(lungs and intestines) is presented, as both cases are caused by professional factors. 
Patients were examined in detail with the use of microscopic and mycological (sowing
 material on a nutrient medium) research.
Results and conclusions. When diagnosing, the professional background of the 
patients should be taken into account. The clinical «symptom of dried leaves» 
proposed by us is likely to be of significant importance in establishing the clinical 
diagnosis of onychomycosis caused by A.flavus, and which can serve as a differential 
sign for other fungal infections of the nails. Our experience confirms the effectiveness 
of treating A. skin and nails using the «pulse therapy» method with Orungal and 
confirms its increase under the condition of a combination of systemic action and 
local antifungal activity of the drug Cidipol	
Tags	professional aspergillosis of the skin and nails, diagnosis, «dried leaves» symptom, 
combined treatment with Orungal, Сidipol	
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Publication of the article	«DERMATOLOGY AND VENEREOLOGY» №4(102), 2023 year, 21-24 pages,
	
DOI	10.33743/2308-1066-2023-4-21-24