Title: CLINICAL AND DIAGNOSTIC PARALLELS OF POSTACNE MANIFESTATIONS
Author: Кондакова
Last saved by: Nancy

ASSOCIATION OF HERPES SIMPLEX VIRUSIS (TYPE 1 AND 2) AND BACTERIAL SEXUALLY TRANSMITTED INFECTIONS

About the author:

G.I. Mavrov, T.V. Osinska, S.К. Dzhoraeva, H.V. Shchogoleva, I.V. Kalashnikovа, 
T.V. Gubenko

Heading | original research
Type of article | Scientific Article

Annotation

Herpes simplex virus infections (HSV; Herpes simplex 1 and 2) are one of the most 
common sexually transmitted viral infections (STIs). Epidemiological and etiological 
factors of human HSV-infections are insufficiently studied, in particular, due to the 
optional registration in Ukraine. 
The objective was to evaluate the prevalence and etiological aspects of HSV-infection
(Herpes simplex 1 and 2) association with somebacterial STIs (Treponema pallidum
, Chlamydia trachomatis, Ureaplasma urealyticum, Trichomonas vaginalis), taking
Into account shifts in the microbiocenosis of the lower genital tract,  as well as 
the psycho-emotional state of patients.
Materials and methods.Markers of HSV-1 and HSV-2 were detected of specific 
antiherpetic antibodies (IgM and IgG) in the serum (plasma) (reagent sets VectoVPG
–IgM, VectoVPG-1-IgG, VectoVPG-2-IgG) in 90 patients (43 men (mean age–41.2 
years) and 47 women(meanage–34.7 years) with STIs (T. pallidum,  Ch. trachomatis, 
U. urealyticum, T. vaginalis) and opportunistic microflora . Assessment of 
psychoemotional state patients was performed using the Hospital Anxiety and 
Depression Scale (HADS) and statistical processing was performed using the 
STATISTICA 9.0 package (StatSoft).
Results.The incidence of STIs caused by HSV -1/2 among the population of
Ukraine is gradually increasing and according to extrapolated  data ( lack of 
official registration) the true intensive rate per 1 year is 100–120 newly 
diagnosed  cases per 100,000 populations. There are gender features (the 
prevalence of markers of HSV-1 among patients with urogenital pathology is 91.5% 
in women and 97.7% in men, HSV2–in 28.8% and 18.6%, respectively) with maximum 
infection is in reproductive age. The associations with STIs are following: Ch. 
trachomatis (up to 29%), U. urealyticum (up to 22%), T. vaginalis ( up to 9%), T. 
pallidum (up to 6%) and opportunistic microflora (up to 26%). When assessing 
the psycho-emotional state of patients with HSV, the clinical severity of anxiety 
and depression was correlated with the duration of the disease, the frequency 
of episodes of exacerbation and the presence of a rash on the genitals.
Conclusions.The modern management or sexually transmitted HSV should
Take into account gender and  age,  etiological aspects ,  be  coercive with 
the modern data of microbiology, namely bacterial and viral associations of STIs, 
as well as with psycho-emotional state of patients.

Tags

Herpes simplex 1 (HSV-1), Herpes simplex 2 (HSV-2), Treponema pallidum, 
Chlamydia trachomatis, Ureaplasma urealyticum, Trichomonas vaginalis, 
opportunistic microflora.

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Publication of the article

«DERMATOLOGY AND VENEREOLOGY» №1(91), 2021 year, 30-35 pages,
 index UDK 616.972–085: 618.12–002–022.7: 579.882.111–036–078

DOI | DOI: 10.33743/2308-1066-2021-1-30-35