TREATMENT OF FUNGAL INFECTION AT THE PRESENT STAGE
About the author:	K.G. Suprun, I.O. Oliinyk	
Heading	clinical observations	
Type of article	Research Article	
Annotation	The objective was to study the therapeutic efficacy of Exik («Vishpha») in the
 treatment of fungal infections.Materials and methods. 37 patients from 22 to 65 years
 old, among them 13 men and 24 women suffering from dermatomycoses,namely: 
varicoloured lichen – 11 patients, smooth skin rubromycosis – 3, foot mycosis – 13,
 inguinal epidermophytosis – 3, candidiasis of large folds – 7 were under observation
 in the clinic of the SE «Institute of Dermatology and Venereology of the NAMS of 
Ukraine».Prior to treatment, all patients underwent laboratory confirmation of the 
diagnosis and then once a week. The treatment was carried outwith Exik cream 
containing 1% naftifine hydrochloride and Exik spray containing 1% naftifine
 hydrochloride according to the instructions.
Results. Of 13 patients with foot mycoses, in 8 people at the end of the second 
week after the start of therapy, clinical and mycological recovery occurred, in 2 – by 
the end of the 3rd week, in 2 – by the end of the 4th. Of the 3 patients with inguinal 
epidermophytosis, by the end of the 2nd week clinical and mycological cure in 2 
patients occurred, by the end of the 3rd week – in 1. Of the 3 patients with
smooth skin rubromycosis, by the end of the 2nd week there clinical and mycological 
cure in one patient who adhered to the recommendations by epilation of lesions, in 2
 patients mycological cure and complete recovery was noted at the 4th week. With the
 lesions of large folds (7 people), complete clinical and mycological cure was 
observed in one patient by the end of the 3rd week, and in 6 by the end of the 4th
 week. When observing patients with multi­colored lichen (11 people), it was found
 that complete clinical and mycological recovery was observed in 6 patients by the 
end of the 2nd week, in 2 – by the end of the 3rd, in 1 – the 4th week, in 2–5 weeks.
Conclusion. Antifungal topical preparations containing 1% naftifine hydrochloride in
 the form of a cream and spray (Exik, «Vishfa») are effective drugs in the treatment 
of foot mycoses and dermatomycoses. The drugs do not have local irritating and 
allergic reactions with external use, have cosmetic advantages. Drugs are 
recommended for primary and secondary prevention of dermatomycosis and foot
mycosis, as well as to prevent relapse of the disease.	
Tags	 naftifine hydrochloride, Exik, dermatomycosis, foot mycoses	
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Publication of the article	«DERMATOLOGY AND VENEREOLOGY» №2(88), 2020 year, 24-28 pages,
 index UDK 616.992.282	
DOI	10.33743/2308-1066-2020-2-24-28